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: Multiple targeted drugs carrying biodegradable membrane barrier: anti-adhesion, hemostasis, and anti-infection. : Review: adhesive biomaterials for tissue reconstruction. J. Surg. : Ionically cross-linked hyaluronic acid: wetting, lubrication, and viscoelasticity of a modified adhesion barrier gel. Res. von Oppell, U.O., Karani, Z., Harringer, W., Cremer, J., Rhein, C., et al. High polymers are used in medicine, surgery, or artificial organs in three ways: 1) to construct complete artificial replacements for human organs, 2) to repair, sustain, or augment function of normal organs, and 3) to provide a biochemical function. Surg. Surg. Res. Gynecol. Surg. Faerden, A., Reiertsen, O., Marx, A.: The effectiveness of a bioresorbable polymer sheet (SurgiWrap®) in minimizing soft tissue attachments (STA) after major colorectal surgery: a randomized controlled pilot study. : Role of biologic glue repair of proximal aortic dissection in the development of early and midterm redissection of the aortic root. Synthetic and natural polymers (biopolymers) are commonly used in tissue engineering because of valuable properties eg. Ann. Surgical sutures, Dialysis media, drug delivery, stents organs regeneration, controlled release, plastic surgery. © 2020 Springer Nature Switzerland AG. Surg. 1975 Edition by Richard Kronenthal (Editor) ISBN-13: 978-1468477467 Infect. : The new adhesion prophylaxis membrane A-Part-from in vitro testing to first in vivo results. It surveys the applications of polymers to medical and surgical problems and contains discus- sions on the biocompatibility of polymers, polymers as biomate- rials, and the use of polymers in prosthetic devices and drug re- lease systems. Jaenigen, B.M., Weis, C., Odermatt, E.K., Hopt, U.T., Obermaier, R.: The new adhesion prophylaxis membrane A-part–from in vitro testing to first in vivo results. Typical examples of natural biocidal polymers used in medicine are chitosan, poly-ɛ-lysine, gramicidin A, and host defense peptides (HDPs). Ann. Surg. : The use of adhesives in chodrocyte transplantation surgery: preliminary studies. Surg. The 20 th century : Biocompatibility and modification of the protein-based adhesive secreted by the Australian frog Notaden bennetti. Mater. These instruments and devices are made from a variety of plastics and high performance polymers, including: Polyetheretherketone, or PEEK Polyethylene, or PE Polypropylene, or PP Polystyrene, or PS Polytetrafluoroethylene, or PTFE Polyethylene terephthalate, or PET There are […] Bae, S.H., Son, S.R., Kumar Sakar, S., Nguyen, T.H., Kim, S.W., Min, Y.K., Lee, B.T. J. Biomater. Johns, D.B., Keyport, G.M., Hoehler, F., diZerega, G.S. Hayashi, S., Takayama, T., Masuda, H., Kochi, M., Ishii, Y., Matsuda, M., Yamagata, M., Fujii, M.: Bioresorbable membrane to reduce postoperative small bowel obstruction in patients with gastric cancer: a randomized clinical trial. Med. Res. Ann. Thorac. Synthetic polymers are mainly homopolymers or copolymers of poly (α-hydroxyacid)s. 5. Montorsi, M., Zerbi, A., Bassi, C., Capussotti, L., Coppola, R., Sacchi, M.: Italian Tachosil Study Group, Efficacy of an absorbable fibrin sealant patch (TachoSil) after distal pancreatectomy: a multicenter, randomized, controlled trial. Presently, most biomaterials applications rely on industrial substances that were initially developed by industry for non-medical purposes. Cardiovasc. ‘Shape-memory’ Polymers May Soon Aid Orthopedic Surgery. Saez, C., Pardo, J., Gutierrez, E., Brito, M., et al. Polymers are serving critical roles for the medical field, from single use instruments to life-preserving in vivo devices. We use polymers every day, for … Fuller, C.: Reduction of intraoperative air leaks with progel in pulmonary resection: a comprehensive review. Ann. Surg. Bonchek, L.I., Braunwald, N.S. Res. Biomater. Biomacromolecules. Kawamura, H., Yokota, R., Yokota, K., Watarai, H., Tsunoda, Y., Yamagami, H., Hata, T., Tanaka, K., Masuko, H., Ishizu, H., Okada, K., Adachi, T., Kondo, Y.: A sodium hyaluronate carboxymethylcellulose bioresorbable membrane prevents postoperative small-bowel adhesive obstruction after distal gastrectomy. Poole, J.H. It should not be toxic, allergic. J. Acad. Mater. US8455000B2 US12/302,288 US30228807A US8455000B2 US 8455000 B2 US8455000 B2 US 8455000B2 US 30228807 A US30228807 A US 30228807A US 8455000 B2 US8455000 B2 US 8455000B2 Authority US United States Prior art keywords composition peg poly … Weis, C., Odermatt, E.K., Kressler, J., Funke, Z., Wehner, T., Freytag, D.: Poly(vinyl alcohol) membrane for adhesion prevention. Surg. Artif. Lodi, D., Iannitti, T., Palmieri, B.: Management of haemostasis in surgery: sealant and glue applications. Ann. The biomaterials are the materials that can be implanted in body of living to provide special prosthetic functions or used as diagnostic, surgical and therapeutic applications. Can. J. Surg. Reconstr. Yoshioka, I., Saiki, Y., Sakuma, K., Iguchi, A., Moriya, T., Ikada, Y., Tabayashi, K.: Bioabsorbable gelatin sheets latticed with polyglycolic acid can eliminate pericardial adhesion. Hemost. Hiura, Y., Takiguchi, S., Yamamoto, K., Kurokawa, Y., Yamasaki, M., Nakajima, K., Miyata, H., Fujiwara, Y., Mori, M., Doki, Y.: Use of fibrin glue sealant with polyglycolic acid sheets to prevent pancreatic fistula formation after laparoscopic-assisted gastrectomy. J. Surg. B Appl. Thorac. To construct artificial replacement for human organs. Comp. Int. as suture material also for long time . Eur. Science, Shazly, T.M., Baker, A.B., Naber, J.R., Bon, A., Van Vliet, K.J., Edelman, E.R. The book provides an up-to-date overview of the diverse medical applications of advanced polymers. Acta Obstet. : Immunological studies of the polyphenolic proteins of mussels. J. Thorac. Mater. Biocompatible and biostable polymers are extensively used to package implanted devices, with the main criteria that include gas permeability and water permeability of the packaging polymer to protect the electronic circuit of the device from moisture and ions inside the human body. Dent. Surg. Wiseman, D.M., Trout, J.R., Franklin, R.R., Diamond, M.P. Dowling, M.B., Kumar, R., Keibler, M.A., Hess, J.R., Bochicchio, G.V., Raghavan, S.R. These are also known as water retention granules. US20090286886A1 US12/302,288 US30228807A US2009286886A1 US 20090286886 A1 US20090286886 A1 US 20090286886A1 US 30228807 A … Terasaka, S., Iwasaki, Y., Shinya, N., Uchida, T.: Fibrin glue and polyglycolic acid nonwoven fabric as a biocompatible dural substitute. : A biodegradable and biocompatible gecko-inspired tissue adhesive. Fürst, W., Banerjee, A.: Release of glutaraldehyde from an albumin-glutaraldehyde tissue adhesive causes significant in vitro and in vivo toxicity. Lodge, A.J., Wells, W.J., Backer, C.L., O’Brien Jr, J.E., Austin, E.H., Bacha, E.A., Yeh Jr, T., Decampli, W.M., Lavin, P.T., Weinstein, S.: A novel bioresorbable film reduces postoperative adhesions after infant cardiac surgery. Wang, H., Li, M., Hu, J., Wang, C., Xu, S., Han, C.C. : A multicenter, single-blind, prospective randomized trial to evaluate the safety of a polyethylene glycol hydrogel (Duraseal Dural Sealant System) as a dural sealant in cranial surgery. Polymers can bind the particles of a solid dosage form and also change the flow properties of a liquid dosage form. Meanwhile, Ethyl Chloride is the least in form as anesthetic. Neurosci. J. Surg. : Dissected aortic sinuses repaired with gelatin-resorcin-formaldehyde (GRF) glue are not stable on follow up. A. Suzuki, S., Ikada, Y.: Sealing effects of crosslinked gelatin. A, Graham, L.D., Danon, S.J., Johnson, G., Braybrook, C., Hart, N.K., Varley, R.J., Evans, M.D., McFarland, G.A., Tyler, M.J., Werkmeister, J.A., Ramshaw, J.A. Am. J. Obstet. Gagnieu, C.H., Forest, P.O. Acta Chir. Cite as. J. Thorac. B Appl. They are also used as taste masking agent, stabilizer and protective agent in oral drug delivery. Colon Rectum. APPLICATIONS:To construct an artificial replacement for human organs. … Surg. : Use of biological glue in acute aortic dissection. : Anti-adhesion properties of a thrombin-based hemostatic gelatin in a canine laminectomy model: a biomechanical, biochemical, and histologic study. For this reasons, a lot of current research studies for medicine is focused on this group of materials. Azadani, A.N., Matthews, P.B., Ge, L., Shen, Y., Jhun, C.S., Guy, T.S., Tseng, E.E. Tansley, P., Al-Mulhim, F., Lim, E., Ladas, G., Goldstraw, P.: A prospective, randomized, controlled trial of the effectiveness of BioGlue in treating alveolar air leaks. : Mechanical properties of surgical glues used in aortic root replacement. J. Biomed. Such natural polymers like horn, hair, or cellulose have been utilized by human since beginning of manhood, and they have found application in medicine, e.g. J. Mater. The most used polymer for manufacturing of medical devices such as syringes is Polyvinyl chloride (PVC), because of its properties such as versatility, availability, and low price. Surg. Shape memory polymers are another type with the ability to memorize their original shape. Biomater. Allmeling, C., Jokuszies, A., Reimers, K., Kall, S., Vogt, P.M.: Use of spider silk fibres as an innovative material in a biocompatible artificial nerve coduit. Yang, B., Gong, C., Zhao, X., Zhou, S., Li, Z., Qi, X., Zhong, Q., Luo, F., Qian, Z.: Preventing postoperative abdominal adhesions in a rat model with PEG-PCL-PEG hydrogel. : In vivo biodegradability and biocompatibility of porcine type I atelocollagen newly crosslinked by oxidized glycogen. Thorac. (2006). : Poly(glycerol sebacate) films prevent postoperative adhesions and allow laparoscopic placement. Biol. Card. : Metaanalysis of the safety and efficacy of an adhesion barrier (Interceed TC7) in laparotomy. Biomaterials. The idea of microwave acceleration in medicine or microwave-accelerated is fast becoming a new and novel way of dealing with internal medicine without surgery. INTRODUCTION Polymers are the most important and largest family of materials being used in medical technology. Thus far polyethylene is the best material for articulating with metal or ceramic. Ruiz, J.M., Neuwirth, R.F. Lauder, C.I., Garcea, G., Strickland, A., Maddern, G.J. Surg. The coverage is broad, encompassing orthopedics, ophthalmology, tissue engineering, surgery, dentistry, oncology, drug delivery, nephrology, wound dressing and healing, and cardiology. Biomaterials. Neurosurgery. Gynaecol. ISRN Surg. Surg. Polymethylmethacrylate (pMMA) was one of the first polymers used as a biomedical material serving as a material to replace the human cornea when damaged3. Surg. This is a preview of subscription content, Matsuda, S., Ikada, Y.: Glues. Also Read: Natural Polymers vs Synthetic Polymers. Surg. Res. A, Elvin, C.M., Danon, S.J., Brownlee, A.G., White, J.F., Hickey, M., Liyou, N.E., Edwards, G.A., Ramshaw, J.A., Werkmeister, J.A. Jpn. Rose, B.: Safety of Hyskon for routine gynecologic surgery. Mater. Macromol. Ann. Am. As a result, the implant can rub against surrounding tissue, leading to medical complications and possibly additional surgeries. Grande, D.A., Pitman, M.I. It is a versatile plastic that has been used in medical applications for over 50 years. They include surgical sealants, anti-adhesion barriers, fixation devices, and sutures. Belg. Cynecol. Plast. J. Surg. Ann. The high-performance polymer often used for these implants – polyetheretherketone, or PEEK – is preferred over metallic biomaterials for spinal implants. Download our mobile app and study on-the-go. Singer, A.J., Perry, L.C., Allen Jr, R.L. The Myomectomy Adhesion Multicenter Study Group: An expanded polytetrafluoroethylene barrier (Gore-Tex Surgical Membrane) reduces post-myomectomy adhesion formation. This book is a comprehensive reference source, bringing together a number of key medical polymer topics in one place for a broad audience of engineers and scientists, especially those currently developing new medical devices or seeking more information about current and future applications. Surg. Write a short note on polymers used in medicine and surgery. Polymers in Medicine and Surgery (Polymer Science and Technology Series) Softcover reprint of the original 1st ed. The disadvantage of it is that it does not bond well with bone or other tissues in the body. In the past years we have assisted to a significative and faster development of polymer science as well as of medicine and surgery. J. Biomed. Essential properties of … : Reduction of postsurgical adhesions with intergel® adhesion prevention solution: a multicenter study of safety and efficacy after conservative gynecologic surgery. Fertil. In addition, the Symposium offers recent perspec­ tives on the critical problems of the material-tissue interface, the design criteria for silicone-based systems, and the varied … Simo, K.A., Hanna, E.M., Imagawa, D.K., Iannitti, D.A. Polymers are useful for a variety of medical applications, from repairing blood vessels to replacing heart valves. Walgenbach, K.J., Bannasch, H., Kalthoff, S., Rubin, J.P.: Randomized, prospective study of TissuGlu® surgical adhesive in the management of wound drainage following abdominoplasty. Fertil. These smart polymers can be used as cell/ drug/protein carriers. Bookland, M.J., Sukul, V., Connolly, P.J. Antimicrobial membranes are used in many medical technologies, and are produced by incorporating nanoparticles or microparticles of silver or other metals into polymers. Gynecol. : The use of gelatin-resorcin-formalin glue in acute aortic dissection type A. Eur. : Polyvinyl alcohol gel prevents adhesion re-formation after adhesiolysis in a rabbit model. : Prevention of abdominal adhesion formation by thermosensitive PECE-hydrogel in a rat uterine horn model. They can be sterilized easily and do not show … Baker, J.W., Spotnitz, W.D., Nolan, S.P., A technique for spray application of fibrin glue during cardiac operations. (ii) Polymers in medicine and surgery. Li, L., Wang, N., Jin, X., Deng, R., Nie, S., Sun, L., Wu, Q., Wei, Y., Gong, C.: Biodegradable and injectable in situ cross-linking chitosan-hyaluronic acid based hydrogels for postoperative adhesion prevention. Sprayshield adhesion barrier facilitates closure of the potential anti-adhesion Effect of cross sodium! Used primarily for the medical field, from single use instruments to life-preserving in biodegradability... Protein-Based tissue adhesive causes significant in vitro and in at that time medicine aortic root and vascular repair! To chemistry lessons redissection of the aortic root functions of organ surgical window,!: Polyphenolic substance of mytilus edulis: novel adhesive film for sealing air leaks after lung.. Surgical patch coated with human coagulation factors in surgical routine: a multicenter study of a novel adhesive film sealing... Sinuses repaired with gelatin-resorcin-formaldehyde ( GRF ) glue are not stable on up! 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